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Coverage and Recovery of Upstream Protein Fractionation Methods in LC-MS/MS Workflows
The proteome of any cell or even any subcellular fraction remains too complex for complete analysis by one dimension of liquid chromatography-tandem mass spectrometry (LC-MS/MS). Hence, to achieve greater depth of coverage for a proteome of interest, most groups routinely subfractionate the sample p...
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Association of Biomolecular Resource Facilities
2011
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3186557/ |
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