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On-Line Electrochemistry/MS - A Powerful Tool for Rapid Prediction of Phase I and II Drug Metabolism

The use of Electrochemsiry is a complementary approach to traditional methods such as in vivo (human, rodent) or in vitro (liver microsomes) metabolism studies, and delivers the oxidative metabolic fingerprint of a (drug) molecule in a very short time. The acquired mass spectra are presented in simp...

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Bibliografiske detaljer
Main Authors: Purkerson, J., Kraj, A., Eysberg, M., Chervet, J.P., Powers, J.
Format: Artigo
Sprog:Inglês
Udgivet: Association of Biomolecular Resource Facilities 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186456/
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