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Simulating Oxidative Metabolism Using On-Line Electrochemistry/Mass Spectrometry

RP-61 The knowledge of the metabolic pathways and the biotransformation of new drugs are crucial for elucidation of degradation routes of new active compounds, especially in the area of possible toxicity. In vitro studies are based on incubating drug candidates with e.g., liver cells (in microsomes...

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Auteurs principaux: Kraj, A., Brouwer, H.J., Purkerson, J., Eysberg, M.
Format: Artigo
Langue:Inglês
Publié: Association of Biomolecular Resource Facilities 2010
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918220/
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