Development of thymic NK cells from double negative 1 thymocyte precursors

The differentiation of natural killer (NK) cells and a subpopulation of NK cells which requires an intact thymus, that is, thymic NK cells, is poorly understood. Previous in vitro studies indicate that double negative (CD4(−)CD8(−), DN) thymocytes can develop into cells with NK cell markers, but the...

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Bibliografiske detaljer
Main Authors: Vargas, Claudia L., Poursine-Laurent, Jennifer, Yang, Liping, Yokoyama, Wayne M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2011
Fag:
Immunobiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186333/
https://ncbi.nlm.nih.gov/pubmed/21821702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-06-359679
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