The Wiskott-Aldrich syndrome protein permits assembly of a focused immunological synapse enabling sustained T-cell receptor signaling

BACKGROUND: T-cell activation relies on the assembly of the immunological synapse, a structure tightly regulated by the actin cytoskeleton. The precise role of the Wiskott-Aldrich syndrome protein, an actin cytoskeleton regulator, in linking immunological synapse structure to downstream signaling re...

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Detalhes bibliográficos
Main Authors: Calvez, Ronan, Lafouresse, Fanny, De Meester, Julie, Galy, Anne, Valitutti, Salvatore, Dupré, Loïc
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2011
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186301/
https://ncbi.nlm.nih.gov/pubmed/21659358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.040204
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