Lataa...
Genetic Variants in Cytosolic 5′-Nucleotidase II Are Associated with Its Expression and Cytarabine Sensitivity in HapMap Cell Lines and in Patients with Acute Myeloid Leukemia
Cytosolic 5′-nucleotidase II (NT5C2) is involved in the development of 1-β-d-arabinofuranosylcytosine (ara-C) resistance and has been associated with clinical outcome in patients receiving ara-C-based chemotherapy. NT5C2 inactivates ara-C by dephosphorylating ara-C monophosphate to ara-C. In this st...
Tallennettuna:
| Päätekijät: | , , , , , , , , , , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
The American Society for Pharmacology and Experimental Therapeutics
2011
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3186292/ https://ncbi.nlm.nih.gov/pubmed/21712425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.182873 |
| Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|