Wird geladen...

Pharmacokinetic Optimization of 4-Substituted Methoxybenzoyl-aryl-thiazole and 2-Aryl-4-benzoyl-imidazole for Improving Oral Bioavailability

Microtubules are critical components of the cytoskeleton. Perturbing their function arrests the growth of a broad spectrum of cancer cell lines, making microtubules an excellent and established target for chemotherapy. All of the U.S. Food and Drug Administration-approved antitubulin agents bind to...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Li, Chien-Ming, Chen, Jianjun, Lu, Yan, Narayanan, Ramesh, Parke, Deanna N., Li, Wei, Ahn, Sunjoo, Miller, Duane D., Dalton, James T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Pharmacology and Experimental Therapeutics 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186212/
https://ncbi.nlm.nih.gov/pubmed/21742898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.110.036616
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!