Proteomic Analyses Reveal an Acidic Prime Side Specificity for the Astacin Metalloprotease Family Reflected by Physiological Substrates

Astacins are secreted and membrane-bound metalloproteases with clear associations to many important pathological and physiological processes. Yet with only a few substrates described their biological roles are enigmatic. Moreover, the lack of knowledge of astacin cleavage site specificities hampers...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Becker-Pauly, Christoph, Barré, Olivier, Schilling, Oliver, auf dem Keller, Ulrich, Ohler, Anke, Broder, Claudia, Schütte, André, Kappelhoff, Reinhild, Stöcker, Walter, Overall, Christopher M.
Format: Artigo
Langue:Inglês
Publié: The American Society for Biochemistry and Molecular Biology 2011
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186203/
https://ncbi.nlm.nih.gov/pubmed/21693781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M111.009233
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires