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Facile synthesis of nucleoside 5′-(α-P-seleno)-triphosphates and phosphoroselenoate RNA transcription

Phosphoroselenoate RNA (PSe-RNA) is nuclease resistant and has great potentials in X-ray crystal structure and function studies of noncoding RNAs and protein–RNA interactions. In order to conveniently synthesize PSe-RNA via transcription, we have developed a one-pot synthetic method for the nucleosi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lin, Lina, Caton-Williams, Julianne, Kaur, Manindar, Patino, Andres M., Sheng, Jia, Punetha, Jaya, Huang, Zhen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185924/
https://ncbi.nlm.nih.gov/pubmed/21873462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2719311
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