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Deep sequencing of microRNA precursors reveals extensive 3′ end modification
MicroRNAs (miRNAs) are small, noncoding RNAs that post-transcriptionally regulate gene expression. An emerging mechanism to control miRNA production is the addition of an oligo-uridine tail to the 3′ end of the precursor miRNA. This has been demonstrated for the Let-7 family of miRNAs in embryonic c...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2011
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3185913/ https://ncbi.nlm.nih.gov/pubmed/21849429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2713611 |
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