Connexin channels provide a target to manipulate brain endothelial calcium dynamics and blood–brain barrier permeability

The cytoplasmic Ca(2+) concentration ([Ca(2+)](i)) is an important factor determining the functional state of blood–brain barrier (BBB) endothelial cells but little is known on the effect of dynamic [Ca(2+)](i) changes on BBB function. We applied different agonists that trigger [Ca(2+)](i) oscillati...

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Main Authors: De Bock, Marijke, Culot, Maxime, Wang, Nan, Bol, Mélissa, Decrock, Elke, De Vuyst, Elke, da Costa, Anaelle, Dauwe, Ine, Vinken, Mathieu, Simon, Alexander M, Rogiers, Vera, De Ley, Gaspard, Evans, William Howard, Bultynck, Geert, Dupont, Geneviève, Cecchelli, Romeo, Leybaert, Luc
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2011
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185887/
https://ncbi.nlm.nih.gov/pubmed/21654699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2011.86
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