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Cyclophilin Inhibitors as a Novel HCV Therapy

A critical role of Cyclophilins, mostly Cyclophilin A (CyPA), in the replication of HCV is supported by a growing body of in vitro and in vivo evidence. CyPA probably interacts directly with nonstructural protein 5A to exert its effect, through its peptidyl-prolyl isomerase activity, on maintaining...

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Bibliographic Details
Main Author: Tang, Hengli
Format: Artigo
Language:Inglês
Published: Molecular Diversity Preservation International (MDPI) 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185723/
https://ncbi.nlm.nih.gov/pubmed/21994697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v2081621
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