Candidate tumor suppressor HYAL2 is a glycosylphosphatidylinositol (GPI)-anchored cell-surface receptor for jaagsiekte sheep retrovirus, the envelope protein of which mediates oncogenic transformation

Jaagsiekte sheep retrovirus (JSRV) can induce rapid, multifocal lung cancer, but JSRV is a simple retrovirus having no known oncogenes. Here we show that the envelope (env) gene of JSRV has the unusual property that it can induce transformation in rat fibroblasts, and thus is likely to be responsibl...

Полное описание

Библиографические подробности

Опубликовано в::	Proc Natl Acad Sci U S A
Главные авторы:	Rai, Sharath K., Duh, Fuh-Mei, Vigdorovich, Vladimir, Danilkovitch-Miagkova, Alla, Lerman, Michael I., Miller, A. Dusty
Формат:	Artigo
Язык:	Inglês
Опубликовано:	National Academy of Sciences 2001
Предметы:	Biological Sciences
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC31854/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11296287/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.071572898
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