Candidate tumor suppressor HYAL2 is a glycosylphosphatidylinositol (GPI)-anchored cell-surface receptor for jaagsiekte sheep retrovirus, the envelope protein of which mediates oncogenic transformation

Jaagsiekte sheep retrovirus (JSRV) can induce rapid, multifocal lung cancer, but JSRV is a simple retrovirus having no known oncogenes. Here we show that the envelope (env) gene of JSRV has the unusual property that it can induce transformation in rat fibroblasts, and thus is likely to be responsibl...

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Rai, Sharath K., Duh, Fuh-Mei, Vigdorovich, Vladimir, Danilkovitch-Miagkova, Alla, Lerman, Michael I., Miller, A. Dusty
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2001
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC31854/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11296287/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.071572898
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!