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Sputum Inflammatory Cells from Persons with Allergic Rhinitis and Asthma Have Decreased Inflammasome Gene Expression
Deficits in inflammasomes, a key element of innate immunity, confer increased susceptibility to infection. We report that sputum cells from asthmatics have decreased expression of inflammasome factors, consistent with reports of increased infection risk in asthmatics.
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3185200/ https://ncbi.nlm.nih.gov/pubmed/21868073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2011.08.012 |
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