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Sputum Inflammatory Cells from Persons with Allergic Rhinitis and Asthma Have Decreased Inflammasome Gene Expression

Deficits in inflammasomes, a key element of innate immunity, confer increased susceptibility to infection. We report that sputum cells from asthmatics have decreased expression of inflammasome factors, consistent with reports of increased infection risk in asthmatics.

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Detalhes bibliográficos
Main Authors: Brickey, Willie June, Alexis, Neil E., Hernandez, Michelle L., Reed, William, Ting, Jenny PY., Peden, David B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185200/
https://ncbi.nlm.nih.gov/pubmed/21868073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2011.08.012
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