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Aging and Amyloid beta-induced oxidative DNA damage and mitochondrial dysfunction in Alzheimer's Disease: Implications for early intervention and therapeutics

Alzheimer's disease (AD) is an age-related progressive neurodegenerative disease affecting thousands of people in the world and effective treatment is still not available. Over two decades of intense research using AD postmortem brains, transgenic mouse and cell models of amyloid precursor prot...

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Detalhes bibliográficos
Main Authors: Mao, Peizhong, Reddy, P. Hemachandra
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185172/
https://ncbi.nlm.nih.gov/pubmed/21871956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2011.08.005
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