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Resuscitating cancer immunosurveillance: selective stimulation of DLL1-Notch signaling in T cells rescues T cell function and inhibits tumor growth
Deficiencies in immune function that accumulate during cancer immunoediting lead to a progressive escape from host immune surveillance. Therapies that correct or overcome these defects could have a powerful impact on cancer management, but current knowledge of the types and mechanisms of immune esca...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3185141/ https://ncbi.nlm.nih.gov/pubmed/21825014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-4366 |
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