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Splice Variants of mda-7/IL-24 Differentially Affect Survival and Induce Apoptosis in U2OS Cells: Functional Characterization of mda-7/IL-24 Splice Isoforms

Interleukin-24 (mda-7/IL-24) is a cytokine in the IL-10 family that has received a great deal of attention for its properties as a tumor suppressor and as a potential treatment for cancer. In this study, we have identified and characterized five alternatively spliced isoforms of this gene. Several,...

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Detalhes bibliográficos
Main Authors: Whitaker, Erin L., Filippov, Valery, Filippova, Maria, Guerrero-Juarez, Christian F., Duerksen-Hughes, Penelope J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185131/
https://ncbi.nlm.nih.gov/pubmed/21843952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2011.07.020
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