Loss of Glucocorticoid Receptor Expression by DNA Methylation Prevents Glucocorticoid Induced Apoptosis in Human Small Cell Lung Cancer Cells

Human small cell lung cancer (SCLC) is highly aggressive, and quickly develops resistance to therapy. SCLC cells are typically insensitive to glucocorticoids due to impaired glucocorticoid receptor (GR) expression. This is important as we have previously shown that expression of a GR transgene induc...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Kay, Paul, Schlossmacher, George, Matthews, Laura, Sommer, Paula, Singh, Dave, White, Anne, Ray, David
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3184945/
https://ncbi.nlm.nih.gov/pubmed/21984896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024839
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares