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Mild elevation of body temperature reduces tumor interstitial fluid pressure and hypoxia, and enhances efficacy of radiotherapy in murine tumor models

Patient and rodent solid tumors often exhibit elevated interstitial fluid pressure (IFP). This condition is recognized as a prognostic indicator for reduced responses to therapy and decreased disease-free survival. Here we tested whether induction of a thermoregulatory-mediated rise in tissue blood...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Sen, Arindam, Capitano, Maegan L., Spernyak, Joseph A., Schueckler, John T., Thomas, Seneca, Singh, Anurag K., Evans, Sharon S., Hylander, Bonnie L., Repasky, Elizabeth A.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2011
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3184616/
https://ncbi.nlm.nih.gov/pubmed/21512134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-4482
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