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Sensorimotor Gating Depends on Polymorphisms of the Serotonin-2A Receptor and Catechol-O-Methyltransferase, but Not on Neuregulin-1 Arg38Gln Genotype: A Replication Study

BACKGROUND: Prepulse inhibition (PPI) of the acoustic startle response (ASR) is an operational measure of sensorimotor gating and a promising endophenotype of schizophrenia. We have recently shown that the linked serotonin-2A receptor (5-HT(2A)R) A-1438 G and T102C polymorphisms modulate PPI in schi...

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Bibliographische Detailangaben
Hauptverfasser: Quednow, Boris B., Schmechtig, Anne, Ettinger, Ulrich, Petrovsky, Nadine, Collier, David A., Vollenweider, Franz X., Wagner, Michael, Kumari, Veena
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3184478/
https://ncbi.nlm.nih.gov/pubmed/19545856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2009.05.007
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