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SPARC Mediates Src-induced Disruption of Actin Cytoskeleton via Inactivation of Small GTPases Rho-Rac-Cdc42

The matricellular glycoprotein Secreted Protein Acidic and Rich in Cysteine (SPARC) plays an important role in the regulation of cell adhesion and proliferation as well as in tumorigenesis and metastasis. Earlier, we reported that, in addition to its potent anti-angiogenic functions, SPARC also indu...

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Detalhes bibliográficos
Main Authors: Bhoopathi, Praveen, Gond, Christopher S., Gujrati, Meena, Dinh, Dzung H, Lakka, Sajani S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3184354/
https://ncbi.nlm.nih.gov/pubmed/21798346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2011.07.008
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