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Molecular dynamics of spermine-DNA interactions: sequence specificity and DNA bending for a simple ligand.

We used molecular dynamics to model interactions between the physiologically important polyamine spermine and two B-DNA oligomers, the homopolymer (dG)10-(dC)10 and the heteropolymer (dGdC)5-(dGdC)5. Water and counterions were included in the simulation. Starting coordinates for spermine-DNA complex...

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Bibliografiset tiedot
Julkaisussa:Nucleic Acids Res
Päätekijät: Feuerstein, B G, Pattabiraman, N, Marton, L J
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 1989
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC318419/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2780313/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/17.17.6883
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