LITAF Mediation of Increased TNF-α Secretion from Inflamed Colonic Lamina Propria Macrophages

Dysregulation of TNF-α in lamina propria macrophages (LPM) is a feature of inflammatory bowel diseases (IBD). LPS-Induced-TNF-Alpha-Factor (LITAF) is a transcription factor that mediates TNF-α expression. To determine whether LITAF participates in the mediation of TNF-α expression in acutely inflame...

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Main Authors: Bushell, Kristen N., Leeman, Susan E., Gillespie, Earl, Gower, Adam C., Reed, Karen L., Stucchi, Arthur F., Becker, James M., Amar, Salomon
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3184169/
https://ncbi.nlm.nih.gov/pubmed/21984950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025849
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