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LPS-induced TNF-α factor (LITAF)-deficient mice express reduced LPS-induced cytokine: Evidence for LITAF-dependent LPS signaling pathways

Previously we identified a transcription factor, LPS-Induced TNF-α Factor (LITAF), mediating inflammatory cytokine expression in LPS-induced processes. To characterize the role of LITAF in vivo, we generated a macrophage-specific LITAF-deficient mouse (macLITAF(−/−)). Our data demonstrate that in ma...

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Detalhes bibliográficos
Main Authors: Tang, Xiaoren, Metzger, Daniel, Leeman, Susan, Amar, Salomon
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1560089/
https://ncbi.nlm.nih.gov/pubmed/16954198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605988103
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