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Imaging Mass Spectrometry Reveals Elevated Nigral Levels of Dynorphin Neuropeptides in L-DOPA-Induced Dyskinesia in Rat Model of Parkinson's Disease

L-DOPA-induced dyskinesia is a troublesome complication of L-DOPA pharmacotherapy of Parkinson's disease and has been associated with disturbed brain opioid transmission. However, so far the results of clinical and preclinical studies on the effects of opioids agonists and antagonists have been...

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Bibliografski detalji
Glavni autori: Ljungdahl, Anna, Hanrieder, Jörg, Fälth, Maria, Bergquist, Jonas, Andersson, Malin
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3184165/
https://ncbi.nlm.nih.gov/pubmed/21984936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025653
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