Induction of Eosinophil Apoptosis by the Cyclin-Dependent Kinase Inhibitor AT7519 Promotes the Resolution of Eosinophil-Dominant Allergic Inflammation

BACKGROUND: Eosinophils not only defend the body against parasitic infection but are also involved in pathological inflammatory allergic diseases such as asthma, allergic rhinitis and contact dermatitis. Clearance of apoptotic eosinophils by macrophages is a key process responsible for driving the r...

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Main Authors: Alessandri, Ana L., Duffin, Rodger, Leitch, Andrew E., Lucas, Christopher D., Sheldrake, Tara A., Dorward, David A., Hirani, Nik, Pinho, Vanessa, de Sousa, Lirlândia Pires, Teixeira, Mauro M., Lyons, John F., Haslett, Christopher, Rossi, Adriano G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3184151/
https://ncbi.nlm.nih.gov/pubmed/21984938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025683
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