Practical Tools to Implement Massive Parallel Pyrosequencing of PCR Products in Next Generation Molecular Diagnostics

Despite improvements in terms of sequence quality and price per basepair, Sanger sequencing remains restricted to screening of individual disease genes. The development of massively parallel sequencing (MPS) technologies heralded an era in which molecular diagnostics for multigenic disorders becomes...

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Detalhes bibliográficos
Main Authors: De Leeneer, Kim, De Schrijver, Joachim, Clement, Lieven, Baetens, Machteld, Lefever, Steve, De Keulenaer, Sarah, Van Criekinge, Wim, Deforce, Dieter, Van Nieuwerburgh, Filip, Bekaert, Sofie, Pattyn, Filip, De Wilde, Bram, Coucke, Paul, Vandesompele, Jo, Claes, Kathleen, Hellemans, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3184136/
https://ncbi.nlm.nih.gov/pubmed/21980484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025531
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