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Mammalian ChlR1 has a role in heterochromatin organization

The ChlR1 DNA helicase, encoded by DDX11 gene, which is responsible for Warsaw breakage syndrome (WABS), has a role in sister-chromatid cohesion. In this study, we show that human ChlR1 deficient cells exhibit abnormal heterochromatin organization. While constitutive heterochromatin is discretely lo...

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Detalhes bibliográficos
Main Authors: Inoue, Akira, Hyle, Judith, Lechner, Mark S., Lahti, Jill M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3184000/
https://ncbi.nlm.nih.gov/pubmed/21854770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2011.08.006
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