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Three-dimensional image reconstruction of dephosphorylated smooth muscle heavy meromyosin reveals asymmetry in the interaction between myosin heads and placement of subfragment 2

Regulation of the actin-activated ATPase of smooth muscle myosin II is known to involve an interaction between the two heads that is controlled by phosphorylation of the regulatory light chain. However, the three-dimensional structure of this inactivated form has been unknown. We have used a lipid m...

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Autors principals: Wendt, Thomas, Taylor, Dianne, Trybus, Kathleen M., Taylor, Kenneth
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC31840/
https://ncbi.nlm.nih.gov/pubmed/11287639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.071051098
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