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Treatment with pyrophosphate inhibits uremic vascular calcification

Pyrophosphate, which may be deficient in advanced renal failure, is a potent inhibitor of vascular calcification. To explore its use as a potential therapeutic, we injected exogenous pyrophosphate subcutaneously or intraperitoneally in normal rats and found that their plasma pyrophosphate concentrat...

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Autores principales: O’Neill, W. Charles, Lomashvili, Koba A., Malluche, Hartmut H., Faugere, Marie-Claude, Riser, Bruce L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3183997/
https://ncbi.nlm.nih.gov/pubmed/21124302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2010.461
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