Characterization of Enhanced Monovalent and Bivalent Thrombin DNA Aptamer Binding Using Single Molecule Force Spectroscopy

Thrombin aptamer binding strength and stability is dependent on sterical parameters when used for atomic force microscopy sensing applications. Sterical improvements on the linker chemistry were developed for high-affinity binding. For this we applied single molecule force spectroscopy using two enh...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Neundlinger, Isabel, Poturnayova, Alexandra, Karpisova, Ivana, Rankl, Christian, Hinterdorfer, Peter, Snejdarkova, Maja, Hianik, Tibor, Ebner, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2011
Assuntos:
Spectroscopy, Imaging, and Other Techniques
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3183820/
https://ncbi.nlm.nih.gov/pubmed/21961605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.07.054
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados