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Neuroprotective Potential of Biphalin, Multireceptor Opioid Peptide, Against Excitotoxic Injury in Hippocampal Organotypic Culture

Biphalin is a dimeric opioid peptide that exhibits affinity for three types of opioid receptors (MOP, DOP and KOP). Biphalin is undergoing intensive preclinical study. It was recognized that activation of δ-opioid receptor elicits neuroprotection against brain hypoxia and ischemia. We compare the ef...

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Autori principali: Kawalec, Maria, Kowalczyk, Joanna E., Beresewicz, Malgorzata, Lipkowski, Andrzej W., Zablocka, Barbara
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3183243/
https://ncbi.nlm.nih.gov/pubmed/21842273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-011-0568-1
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