TRIM79α, an interferon-stimulated gene product, restricts tick-borne encephalitis virus replication by degrading the viral RNA polymerase

In response to virus infection, type I interferons (IFNs) induce several genes, most of whose functions are largely unknown. Here we show that the tripartite motif (TRIM) protein, TRIM79α, is an IFN-stimulated gene (ISG) product that specifically targets tick-borne encephalitis virus (TBEV), a Flavi...

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Huvudupphovsmän: Taylor, R. Travis, Lubick, Kirk J., Robertson, Shelly J., Broughton, James P., Bloom, Marshall E., Bresnahan, Wade A., Best, Sonja M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182769/
https://ncbi.nlm.nih.gov/pubmed/21925107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2011.08.004
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