ANGIOTENSIN II UPREGULATES PP2Cα AND INHIBITS AMPK SIGNALING AND ENERGY BALANCE LEADING TO SKELETAL MUSCLE WASTING

Congestive heart failure (CHF) and chronic kidney disease (CKD) are characterized by chronically elevated angiotensin II (Ang II) and muscle wasting. Ang II causes skeletal muscle wasting by reducing appetite and by enhancing catabolism. The serine/threonine kinase 5'-Adenosine Monophosphate Ac...

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Detalhes bibliográficos
Main Authors: Tabony, Alexander Michael, Yoshida, Tadashi, Galvez, Sarah, Higashi, Yusuke, Sukhanov, Sergiy, Chandrasekar, Bysani, Mitch, William E., Delafontaine, Patrice
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182768/
https://ncbi.nlm.nih.gov/pubmed/21844485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.111.174839
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