ANGIOTENSIN II UPREGULATES PP2Cα AND INHIBITS AMPK SIGNALING AND ENERGY BALANCE LEADING TO SKELETAL MUSCLE WASTING

Congestive heart failure (CHF) and chronic kidney disease (CKD) are characterized by chronically elevated angiotensin II (Ang II) and muscle wasting. Ang II causes skeletal muscle wasting by reducing appetite and by enhancing catabolism. The serine/threonine kinase 5'-Adenosine Monophosphate Ac...

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Bibliographische Detailangaben
Hauptverfasser: Tabony, Alexander Michael, Yoshida, Tadashi, Galvez, Sarah, Higashi, Yusuke, Sukhanov, Sergiy, Chandrasekar, Bysani, Mitch, William E., Delafontaine, Patrice
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182768/
https://ncbi.nlm.nih.gov/pubmed/21844485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.111.174839
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