Intermolecular transmission of superoxide dismutase 1 misfolding in living cells

Human wild-type superoxide dismutase-1 (wtSOD1) is known to coaggregate with mutant SOD1 in familial amyotrophic lateral sclerosis (FALS), in double transgenic models of FALS, and in cell culture systems, but the structural determinants of this process are unclear. Here we molecularly dissect the ef...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Grad, Leslie I., Guest, Will C., Yanai, Anat, Pokrishevsky, Edward, O'Neill, Megan A., Gibbs, Ebrima, Semenchenko, Valentyna, Yousefi, Masoud, Wishart, David S., Plotkin, Steven S., Cashman, Neil R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2011
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182705/
https://ncbi.nlm.nih.gov/pubmed/21930926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1102645108
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge