Conformational landscape of the human immunodeficiency virus type 1 reverse transcriptase non-nucleoside inhibitor binding pocket: Lessons for inhibitor design from a cluster analysis of many crystal structures

Clustering of 99 available X-ray crystal structures of HIV-1 reverse transcriptase (RT) at the flexible non-nucleoside inhibitor binding pocket (NNIBP) provides information about features of the conformational landscape for binding non-nucleoside inhibitors (NNRTIs), including effects of mutation an...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Paris, Kristina A., Haq, Omar, Felts, Anthony K., Das, Kalyan, Arnold, Eddy, Levy, Ronald M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182518/
https://ncbi.nlm.nih.gov/pubmed/19827836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm900854h
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados