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cMyc Is a Principal Upstream Driver of β-Cell Proliferation in Rat Insulinoma Cell Lines and Is an Effective Mediator of Human β-Cell Replication

Adult human β-cells replicate slowly. Also, despite the abundance of rodent β-cell lines, there are no human β-cell lines for diabetes research or therapy. Prior studies in four commonly studied rodent β-cell lines revealed that all four lines displayed an unusual, but strongly reproducible, cell cy...

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Detalhes bibliográficos
Main Authors: Karslioglu, Esra, Kleinberger, Jeffrey W., Salim, Fatimah G., Cox, Amy E., Takane, Karen K., Scott, Donald K., Stewart, Andrew F.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182418/
https://ncbi.nlm.nih.gov/pubmed/21885567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2011-1074
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