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Protection of Mice From a Chlamydia trachomatis Vaginal Infection Using a Salicylidene Acylhydrazide, a Potential Microbicide

The salicylidene acylhydrazide INP0341 inhibits growth of Chlamydia in HeLa cells, has negligible cell toxicity, and does not inhibit the growth of lactobacilli. The antichlamydial activity of INP0341 was retained when tested in vaginal and semen simulants. Vaginal tissue from INP0341-treated mice a...

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Détails bibliographiques
Auteurs principaux: Slepenkin, Anatoly, Chu, Hencelyn, Elofsson, Mikael, Keyser, Pia, Peterson, Ellena M.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2011
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182314/
https://ncbi.nlm.nih.gov/pubmed/21933873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir552
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