MCL1 increases primitive thymocyte viability in female mice and promotes thymic expansion into adulthood

Increasing the pool of cells at early T-cell developmental stages enhances thymopoiesis and is especially beneficial when T-cell production is compromised by radiation or aging. Within the immature double-negative (DN; CD4(−)CD8(−)) thymocyte subpopulation, the DN1 subset contains the most primitive...

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Detalhes bibliográficos
Main Authors: Gui, Jingang, Morales, Amanda J., Maxey, Sophie E., Bessette, Katherine A., Ratcliffe, Nora R., Kelly, John A., Craig, Ruth W.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Original Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182299/
https://ncbi.nlm.nih.gov/pubmed/21937457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxr073
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