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RhoB deficiency in thymic medullary epithelium leads to early thymic atrophy

RhoB, a member of the Rho subfamily of small GTPases, mediates diverse cellular functions, including cytoskeletal organization, cell transformation and vesicle trafficking. The thymus undergoes progressive decline in its structure and function after puberty. We found that RhoB was expressed in thymi...

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Détails bibliographiques
Auteurs principaux: Bravo-Nuevo, Arturo, O'Donnell, Rebekah, Rosendahl, Alexander, Chung, Jae Hoon, Benjamin, Laura E., Odaka, Chikako
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2011
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182298/
https://ncbi.nlm.nih.gov/pubmed/21865151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxr064
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