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RhoB deficiency in thymic medullary epithelium leads to early thymic atrophy

RhoB, a member of the Rho subfamily of small GTPases, mediates diverse cellular functions, including cytoskeletal organization, cell transformation and vesicle trafficking. The thymus undergoes progressive decline in its structure and function after puberty. We found that RhoB was expressed in thymi...

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Autors principals: Bravo-Nuevo, Arturo, O'Donnell, Rebekah, Rosendahl, Alexander, Chung, Jae Hoon, Benjamin, Laura E., Odaka, Chikako
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182298/
https://ncbi.nlm.nih.gov/pubmed/21865151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxr064
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