Sun Exposure, Vitamin D Receptor Polymorphisms FokI and BsmI and Risk of Multiple Primary Melanoma

Sunlight exposure increases risk of melanoma. Sunlight also potentiates cutaneous synthesis of vitamin D, which can inhibit melanoma cell growth and promote apoptosis. Vitamin D effects are mediated through the vitamin D receptor (VDR). We hypothesized that genetic variation in VDR affects the relat...

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Main Authors: Mandelcorn-Monson, Rochelle, Marrett, Loraine, Kricker, Anne, Armstrong, Bruce K., Orlow, Irene, Goumas, Chris, Paine, Susan, Rosso, Stefano, Thomas, Nancy, Millikan, Robert C., Pole, Jason D., Cotignola, Javier, Rosen, Cheryl, Kanetsky, Peter A., Lee-Taylor, Julia, Begg, Colin B., Berwick, Marianne
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182291/
https://ncbi.nlm.nih.gov/pubmed/21612999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canep.2011.03.003
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