Sun Exposure, Vitamin D Receptor Polymorphisms FokI and BsmI and Risk of Multiple Primary Melanoma

Sunlight exposure increases risk of melanoma. Sunlight also potentiates cutaneous synthesis of vitamin D, which can inhibit melanoma cell growth and promote apoptosis. Vitamin D effects are mediated through the vitamin D receptor (VDR). We hypothesized that genetic variation in VDR affects the relat...

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Detalhes bibliográficos
Main Authors: Mandelcorn-Monson, Rochelle, Marrett, Loraine, Kricker, Anne, Armstrong, Bruce K., Orlow, Irene, Goumas, Chris, Paine, Susan, Rosso, Stefano, Thomas, Nancy, Millikan, Robert C., Pole, Jason D., Cotignola, Javier, Rosen, Cheryl, Kanetsky, Peter A., Lee-Taylor, Julia, Begg, Colin B., Berwick, Marianne
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182291/
https://ncbi.nlm.nih.gov/pubmed/21612999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canep.2011.03.003
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