Sun Exposure, Vitamin D Receptor Polymorphisms FokI and BsmI and Risk of Multiple Primary Melanoma

Sunlight exposure increases risk of melanoma. Sunlight also potentiates cutaneous synthesis of vitamin D, which can inhibit melanoma cell growth and promote apoptosis. Vitamin D effects are mediated through the vitamin D receptor (VDR). We hypothesized that genetic variation in VDR affects the relat...

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Hauptverfasser: Mandelcorn-Monson, Rochelle, Marrett, Loraine, Kricker, Anne, Armstrong, Bruce K., Orlow, Irene, Goumas, Chris, Paine, Susan, Rosso, Stefano, Thomas, Nancy, Millikan, Robert C., Pole, Jason D., Cotignola, Javier, Rosen, Cheryl, Kanetsky, Peter A., Lee-Taylor, Julia, Begg, Colin B., Berwick, Marianne
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182291/
https://ncbi.nlm.nih.gov/pubmed/21612999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canep.2011.03.003
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