NRF2 Mutation Confers Malignant Potential and Resistance to Chemoradiation Therapy in Advanced Esophageal Squamous Cancer

Esophageal squamous cancer (ESC) is one of the most aggressive tumors of the gastrointestinal tract. A combination of chemotherapy and radiation therapy (CRT) has improved the clinical outcome, but the molecular background determining the effectiveness of therapy remains unknown. NRF2 is a master tr...

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Detalhes bibliográficos
Main Authors: Shibata, Tatsuhiro, Kokubu, Akiko, Saito, Shigeru, Narisawa-Saito, Mako, Sasaki, Hiroki, Aoyagi, Kazuhiko, Yoshimatsu, Yuki, Tachimori, Yuji, Kushima, Ryoji, Kiyono, Tohru, Yamamoto, Masayuki
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182278/
https://ncbi.nlm.nih.gov/pubmed/21969819
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