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VEGFR2 Translocates to the Nucleus to Regulate Its Own Transcription

Vascular Endothelial Growth Factor Receptor-2 (VEGFR2) is the major mediator of the angiogenic effects of VEGF. In addition to its well known role as a membrane receptor that activates multiple signaling pathways, VEGFR2 also has a nuclear localization. However, what VEGFR2 does in the nucleus is st...

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Hlavní autoři: Domingues, Inês, Rino, José, Demmers, Jeroen A. A., de Lanerolle, Primal, Santos, Susana Constantino Rosa
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182252/
https://ncbi.nlm.nih.gov/pubmed/21980525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025668
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