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Acetylation of the Proto-Oncogene EVI1 Abrogates Bcl-xL Promoter Binding and Induces Apoptosis

EVI1 (Ecotropic Viral Integration site I), which was originally identified as a myeloid transforming gene by means of retroviral insertional mutagenesis in mouse leukemia, encodes a nuclear DNA binding zinc finger protein. The presence of zinc fingers that are able to bind to specific sequences of D...

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Autori principali: Pradhan, Anjan Kumar, Mohapatra, Alok Das, Nayak, Kasturi Bala, Chakraborty, Soumen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182211/
https://ncbi.nlm.nih.gov/pubmed/21980434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025370
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