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17β-Estradiol-Mediated Neuroprotection and ERK Activation Require a Pertussis Toxin-Sensitive Mechanism Involving GRK2 and β-Arrestin-1

17-β-Estradiol (E2) is a steroid hormone involved in numerous bodily functions, including several brain functions. In particular, E2 is neuroprotective against excitotoxicity and other forms of brain injuries, a property that requires the extracellular signal-regulated kinase (ERK) pathway and possi...

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Detalhes bibliográficos
Main Authors: Dominguez, Reymundo, Hu, Eric, Zhou, Miou, Baudry, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182118/
https://ncbi.nlm.nih.gov/pubmed/19339617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0550-09.2009
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