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A Bayesian hierarchical nonlinear mixture model in the presence of artifactual outliers in a population pharmacokinetic study
The purpose of this study is to develop a statistical methodology to handle a large proportion of artifactual outliers in a population pharmacokinetic (PK) modeling. The motivating PK data were obtained from a population PK study to examine associations between PK parameters such as clearance of dex...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3182101/ https://ncbi.nlm.nih.gov/pubmed/21847635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10928-011-9211-7 |
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